HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86651783, compound → HCID 66717452, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86651783 | HCID 86651783 | — |
| Reactant | HCID 86651784 | HCID 86651784 | — |
| Product | HCID 66717452 | HCID 66717452 | 66% |
Reaction Steps
Reaction and post-treatment were carried out in the same manner as in Example 22-(d) except for using tert-butyl[tert-butoxycarbonyl(6-{[4-(5-chlorothiazol-2-yl)benzyl](pyridin-2-ylsulfonyl)aminomethyl}pyridin-2-yl)amino]acetate (265 mg, 0.386 mmol) obtained in Example 24-(a) in place of tert-butyl[tert-butoxycarbonyl(6-{[4-(5-methylthiazol-2-yl)benzyl] (pyridin-2-ylsulfonyl)aminomethyl}pyridin-2-yl)-amino]acetate to afford the title compound (135 mg) as a slightly brown solid. (Yield: 66%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648097B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-39539939dc334c7a882e713941e9080f |
| Source note | uspto-grants-2014_02 |