Hydrogen Bromide → HCID 19019164, compound

2-hydroxybutyrolactone, Brit. Pat. No. 688.253 [C A 48, p.3996 (1954)], (5.1 g) was dissolved in 10 ml ethanol and the solution was saturated with hydrogenbromide at 0° C. After standing at room temperature during 66 hours, the solvent was evaporated at a low pressure. The residue was mixed with ice-water and the mixture neutralized with 10% aqueous sodium carbonate. The mixture was then extracted several times with diethyl ether and the combined ether extracts washed with saturated, aqueous sodium sulphate and dried over anhydrous sodium sulphate. After evaporation of the solvent, the residue was distilled at 12 mm Hg. The fraction boiling at 109°-112° C. weighing 3,79 g was used in example 2 below.

1. customthe solvent was evaporated at a low pressure
2. additionThe residue was mixed with ice-water
3. extractionThe mixture was then extracted several times with diethyl ether
4. washthe combined ether extracts washed with saturated, aqueous sodium sulphate
5. dry with materialdried over anhydrous sodium sulphate
6. customAfter evaporation of the solvent
7. distillationthe residue was distilled at 12 mm Hg

ORD record

ord-f5778dbbb52a435c950b7eb7a03ecfb4

Source dataset

uspto-grants-1985_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04495190