Quinoxaline → HCID 13385715, compound

HRID 2412909Notes

Reaction equation

HRID 2412909 reaction equation
[N:1]1[C:10]2C(=CC=C[CH:9]=2)N=[CH:3][CH:2]=1.Cl[C:12]1[C:13]2[N:14]([CH:22]=[N:23][N:24]=2)[C:15]2[C:20]([N:21]=1)=[CH:19][CH:18]=[CH:17][CH:16]=2.[CH2:25](NCC)[CH3:26].C(NCCC)CC>>[CH2:2]([N:1]([CH2:10][CH3:9])[C:12]1[C:13]2[N:14]([C:22]([CH2:25][CH3:26])=[N:23][N:24]=2)[C:15]2[C:20]([N:21]=1)=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH3:3]

Participants

5

Reactant 4

HCID 7045QuinoxalineHCID 8021DiethylamineHCID 8902DipropylamineHCID 11261184-Chloro[1,2,4]triazolo[4,3-a]quinoxaline

Product 1

HCID 13385715HCID 13385715, compoundYield 69%

Procedure

This compound was prepared by the method of Example 11, utilizing 4-chloro-1-ethyl-[1,2,4]triazolo4,3-a]quinoxaline (the product of Example 4) as starting material in place of 4-chloro-[1,2,4]triazolo[4,3-a]quinoxaline (the product of Example 2) and diethylamine as reagent in place of di-n-propylamine. The crude product was recrystallized from cyclohexane to afford 3.54 g. (69% yield) of pure 4-diethylamino-1-ethyl-[1,2,4]triazolo[4,3-a]quinoxaline as a white solid (m.p. 98°-100° C.). Mass spectrum: m/e, 269 (P).

Workup

  1. customThis compound was prepared by the method of Example 11
  2. customThe crude product was recrystallized from cyclohexane
  3. customto afford 3.54 g

Sources & evidence

ORD record
ord-810ed57c196a46d28b00256effcb619b
Source dataset
uspto-grants-1985_01
Patent number
US04495187

Reaction notes

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