反应详情

A mixture of 2.55 g (0.01 mole) of 2,3-bis(4-fluorophenyl)-1H-pyrrole and 1.3 g (0.011 mole) of trifluoroacetaldehyde hydrate in 75 ml toluene was heated at reflux for 3.5 hours. The mixture was concentrated on a rotary evaporator. The residue was purified by chromatography on silica gel to give 1.9 g of product, m.p. 121°-122°.

1. temperaturewas heated
2. temperatureat reflux for 3.5 hours
3. concentrationThe mixture was concentrated on a rotary evaporator
4. customThe residue was purified by chromatography on silica gel