HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,2,2-Trifluoroacetaldehyde hydrate → HCID 13371359, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,2,2-Trifluoroacetaldehyde hydrate | HCID 2781366 | — |
| Reactant | 2,3-bis(4-fluorophenyl)-1H-pyrrole | HCID 11107919 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 13371359 | HCID 13371359 | 53.8% |
Reaction Steps
A mixture of 2.55 g (0.01 mole) of 2,3-bis(4-fluorophenyl)-1H-pyrrole and 1.3 g (0.011 mole) of trifluoroacetaldehyde hydrate in 75 ml toluene was heated at reflux for 3.5 hours. The mixture was concentrated on a rotary evaporator. The residue was purified by chromatography on silica gel to give 1.9 g of product, m.p. 121°-122°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04495196 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-e528328f50bc42528ba376efed36e29d |
| Source note | uspto-grants-1985_01 |