反应详情

According to Method B, the title compound was synthesized from the reaction of 7-(2,3-epoxypropoxy) flavone and 70% aqueous ethylamine followed by treatment with HCl/EtOH, as white prisms, m.p. 244°-46° (MeOH) in 36% yield. The free base was obtained after column purification as white crystals, m.p. 164°-65° (MeOH/ehter), yield 39%.

1. customThe free base was obtained
2. customafter column purification as white crystals, m.p. 164°-65° (MeOH/ehter), yield 39%