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2-Nitropropane → 5-methoxy-3-(2,2-dimethyl-2-nitroethyl)-1H-indole
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 2-Nitropropane | HCID 398 | — |
| 反応物 | 5-Methoxy-N,N-dimethyl-1H-indole-3-methanamine | HCID 27965 | — |
| 生成物 | 5-methoxy-3-(2,2-dimethyl-2-nitroethyl)-1H-indole | HCID 12619662 | — |
反応手順
This material was prepared by the reaction of 5-methoxygramine (Procedure 11B) and 2-nitropropane substantially as described in Procedure 10C. The product was initially recovered as a dark oil which crystallized from i-Pr2O solution after treatment thereof with activated carbon, yield 31.3 g. (from 33 g. of 5-methoxygramine), m.p. 83°-85°. The identity of the product was confirmed by inspection of its NMR spectrum.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04495352 |
| 出典データセット | uspto-grants-1985_01 |
| ORD ID | ord-3961d4c57a6742818b9fe5f8135a5555 |
| 出典メモ | uspto-grants-1985_01 |