Phenol → Phenol, 4-(3-pyridinyl)-

HRID 2413060Notes

Reaction equation

HRID 2413060 reaction equation
N[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:9]=[N:10][CH:11]=[CH:12][CH:13]=2)=[CH:4][CH:3]=1.C1([OH:20])C=CC=CC=1>>[N:10]1[CH:11]=[CH:12][CH:13]=[C:8]([C:5]2[CH:6]=[CH:7][C:2]([OH:20])=[CH:3][CH:4]=2)[CH:9]=1

Participants

3

Reactant 2

HCID 996PhenolHCID 4595224-(Pyridin-3-yl)aniline

Product 1

HCID 153040Phenol, 4-(3-pyridinyl)-

Procedure

Using the procedure described above, 3-(4'-aminophenyl)pyridine (10.0 g, 0.059 mol) is converted to the phenol. A total of 7.66 g of product is obtained, after chromatography, which is then recrystallized from acetone-hexane to give 6.52 g (65% of theory) of off-white crystals which have as melting point of 202°-203° C.

Sources & evidence

ORD record
ord-b6a38669ca8241aabdfa6fdf801419e6
Source dataset
uspto-grants-1985_01
Patent number
US04495357

Reaction notes

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