Hydrogen Bromide → L-isoleucyl-N-(3-pyridyl)glycine hydrobromide

HRID 2413105Notes

Reaction equation

HRID 2413105 reaction equation
C([NH:11][C@H:12]([C:17]([N:19]([C:24]1[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=1)[CH2:20][C:21]([OH:23])=[O:22])=[O:18])[C@H:13]([CH2:15][CH3:16])[CH3:14])(OCC1C=CC=CC=1)=O.[BrH:30]>C(O)(=O)C>[BrH:30].[NH2:11][C@H:12]([C:17]([N:19]([C:24]1[CH:25]=[N:26][CH:27]=[CH:28][CH:29]=1)[CH2:20][C:21]([OH:23])=[O:22])=[O:18])[C@H:13]([CH2:15][CH3:16])[CH3:14]

Participants

4

Reactant 2

HCID 260Hydrogen BromideHCID 54567953N-carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)glycine

Product 1

HCID 70483993L-isoleucyl-N-(3-pyridyl)glycine hydrobromide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

In a manner described in example 5B, N-carbobenzyloxy-L-isoleucyl-N-(3-pyridyl)-glycine was treated with anhydrous hydrogen bromide in acetic acid to yield L-isoleucyl-N-(3-pyridyl) glycine hydrobromide.

Sources & evidence

ORD record
ord-b83f0e78cb0d43548485239636d4e88a
Source dataset
uspto-grants-1985_01
Patent number
US04496542

Reaction notes

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