Isopropylamine → HCID 13269121, compound

Participants

Reaction Conditions

Reaction Steps

38.9 parts by weight of methylamidosulfonyl chloride were added a little at a time to a mixture of 17.7 parts of isopropylamine, 33.3 parts of triethylamine and 120 parts of tetrahydrofuran (THF), which was kept at from -70° to -65° C. The mixture was stirred at 20° C. for 3 hours, the insoluble material was filtered off and the solution was evaporated to dryness. The residue on the filter was extracted by stirring with methylene chloride, the mixture was filtered and the solution was concentrated. 30.6 parts of N-methyl-N'-isopropylsulfamide of melting point 50°-52° C. (starting substance) were obtained.

Provenance & Evidence