Isopropylamine → HCID 13269121, compound

Temperature

20 °C

38.9 parts by weight of methylamidosulfonyl chloride were added a little at a time to a mixture of 17.7 parts of isopropylamine, 33.3 parts of triethylamine and 120 parts of tetrahydrofuran (THF), which was kept at from -70° to -65° C. The mixture was stirred at 20° C. for 3 hours, the insoluble material was filtered off and the solution was evaporated to dryness. The residue on the filter was extracted by stirring with methylene chloride, the mixture was filtered and the solution was concentrated. 30.6 parts of N-methyl-N'-isopropylsulfamide of melting point 50°-52° C. (starting substance) were obtained.

1. customwas kept at from -70° to -65° C
2. filtrationthe insoluble material was filtered off
3. customthe solution was evaporated to dryness
4. extractionThe residue on the filter was extracted
5. stirringby stirring with methylene chloride
6. filtrationthe mixture was filtered
7. concentrationthe solution was concentrated

ORD record

ord-0d96cc5e6b354699b521bd30739e0157

Source dataset

uspto-grants-1985_01

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US04496563