HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetaldehyde → HCID 20430479, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetaldehyde | HCID 177 | — |
| Reactant | 1,8-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-1-(2-fluoroethyl)-4-oxo-7-(1-piperazinyl)- | HCID 3069002 | — |
| Solvent | Formic Acid | HCID 284 | — |
| Product | HCID 20430479 | HCID 20430479 | — |
Reaction Steps
Using 6-fluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxo-7-(1-piperazinyl)-1,8-naphthyridine-3-carboxylic acid as a starting material, by reaction with acetoaldehyde in the presence of formic acid in accordance with the method of Example 1 is obtained 7-(4-ethyl-1-piperazinyl)-6-fluoro-1-(2-fluoroethyl)-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid (compound 2) m.p. 223°-224° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04496566 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-080bc9cb11f64bb4833f5a6086e08a8e |
| Source note | uspto-grants-1985_01 |