HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzenebutanamine → HCID 20430539, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzenebutanamine | HCID 83242 | — |
| Reactant | 3-Pyridylmethyl-2-methylthio-4-pyrimidone | HCID 12783823 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 20430539 | HCID 20430539 | — |
Reaction Steps
A mixture of 4-phenylbutylamine (4.0 g), 2-methylthio-5-(3-pyridylmethyl)-4-pyrimidone (5.8 g) and dry pyridine (40 ml) was heated under reflux for 60 hours and evaporated to dryness. Water was added to the residue and the pH was adjusted to 7 with hydrochloric acid. The solid which separated out was recrystallised from aqueous ethanol to give 2-(4-phenylbutylamino)-5-(3-pyridylmethyl)-4-pyrimidone dihydrate m.p. about 70°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04496567 |
| Source dataset | uspto-grants-1985_01 |
| ORD ID | ord-2c5ee3db23df4fd9af3a2ed953ab5c8a |
| Source note | uspto-grants-1985_01 |