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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2413172Generated: November 2, 2026

5-(3-Methoxybenzyl)-2-methylthio-4-pyrimidone → 2-[2-(3-Dimethylaminomethylbenzylthio)ethylamino]-5-(3-methoxybenzyl)-4-pyrimidone

https://huagongshe.com/reaction/2413172

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(3-Methoxybenzyl)-2-methylthio-4-pyrimidoneHCID 12951526—
Reactant2-[[3-(N,N-Dimethylaminomethyl)phenyl]methylthio]ethanamineHCID 12952019—
SolventPyridineHCID 1049—
Product2-[2-(3-Dimethylaminomethylbenzylthio)ethylamino]-5-(3-methoxybenzyl)-4-pyrimidoneHCID 20430524—

Reaction Steps

Reaction of 2-(3-dimethylaminomethylbenzylthio)ethylamine by heating under reflux for 40 hours in dry pyridine with 5-(3-methoxybenzyl)-2-methylthio-4-pyrimidone gives 2-[2-(3-dimethylaminomethylbenzylthio)ethylamino]-5-(3-methoxybenzyl)-4-pyrimidone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04496567
Source datasetuspto-grants-1985_01
ORD IDord-771e1bd592f04b14b92bd31cf32954f8
Source noteuspto-grants-1985_01