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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2413175Generated: November 1, 2026

5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidone → 2-[2-(3-(Dimethylaminomethyl)benzylthio)ethylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone

https://huagongshe.com/reaction/2413175

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(5,6-Dimethyl-3-pyridylmethyl)-2-nitroamino4-pyrimidoneHCID 12783831—
Reactant2-[[3-(N,N-Dimethylaminomethyl)phenyl]methylthio]ethanamineHCID 12952019—
SolventEthanolHCID 702—
Product2-[2-(3-(Dimethylaminomethyl)benzylthio)ethylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidoneHCID 20430503—

Reaction Steps

Reaction of 2-[3-(dimethylaminomethyl)benzylthio]ethylamine with an equimolar amount of 2-nitroamino-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone by heating under reflux in ethanol for 48 hours gives 2-[2-(3-(dimethylaminomethyl)benzylthio)ethylamino]-5-(5,6-dimethyl-3-pyridylmethyl)-4-pyrimidone.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04496567
Source datasetuspto-grants-1985_01
ORD IDord-a1c6ec4f9f86414b9ab74e9804011d66
Source noteuspto-grants-1985_01