反应详情

A mixture of (1,1'-biphenyl-4-yl)chloro(chloromethyl)methylsilane and two equivalents of imidazole sodium salt in dimethylformamide is warmed to 80°-90° C. for 2 hours. Ten equivalents of methanol is then added, and the mixture is held at 70° for 1 hour, cooled, diluted with water, and quickly extracted with ether. Washing the ether solution with water and brine, drying over magnesium sulfate, and evaporation leaves the title compound.

1. temperatureis warmed to 80°-90° C. for 2 hours
2. temperaturecooled
3. extractionquickly extracted with ether
4. washWashing the ether solution with water and brine
5. dry with materialdrying over magnesium sulfate, and evaporation