HCID 20430445, compound → HCID 20430412, compound

Participants

Reaction Steps

2-Benzhydryloxycarbonyl-3-(2-dimethylamino-thiazol-5-yl)-8-oxo-7-(thien-2-yl-acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene (2.4 g) is treated with formic acid (25 cc) in accordance with the working method described in Example 17, and 2-carboxy-3-(2-dimethylamino-thiazol-5-yl)-8-oxo-7-(thien-2-yl-acetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene (1.05 g) is obtained, as the inner salt, in the form of a yellow solid.

Provenance & Evidence