HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 2666228, compound → 4-Chloro-N-[2-(3-methoxyphenyl)ethyl]aniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 2666228 | HCID 2666228 | — |
| Reactant | Aluminium lithium hydride | HCID 21226445 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 4-Chloro-N-[2-(3-methoxyphenyl)ethyl]aniline | HCID 13361912 | — |
Reaction Steps
22.1 g of N-(4-chlorophenyl)-3-methoxyphenylacetamide are reduced with lithium aluminum hydride in THF. After destroying the reagent with water, filtering, drying and evaporating in a rotary evaporator, the oily residue is taken up in diethyl ether, and the desired product is precipitated as the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04717724 |
| Source dataset | uspto-grants-1988_01 |
| ORD ID | ord-80ec3ea2398249ffbd754073e21528da |
| Source note | uspto-grants-1988_01 |