Cyclohexylamine → HCID 70410985, compound

HRID 2413531Notes

Reaction equation

HRID 2413531 reaction equation
[S:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[N:3]=[C:2]1[S:10][CH2:11][CH:12]([C:19]([O:21]CC)=O)[CH2:13][C:14]([O:16]CC)=O.[CH:24]1([NH2:30])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1>C1(C)C=CC=CC=1>[CH:24]1([NH:30][C:14]([CH2:13][CH:12]([C:19]([NH:3][CH:4]2[CH2:9][CH2:8][CH2:7][CH2:6][CH2:5]2)=[O:21])[CH2:11][S:10][C:2]2[S:1][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=3[N:3]=2)=[O:16])[CH2:29][CH2:28][CH2:27][CH2:26][CH2:25]1

Participants

4

Reactant 2

HCID 7965CyclohexylamineHCID 20154927HCID 20154927, compound

Product 1

HCID 70410985HCID 70410985, compound

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

18.5 parts of diethyl 3-(benzothiazol-2-ylthio)-propane- 1,2-dicarboxylate are stirred with 31.1 parts cyclohexylamine for 12 hours at 95° C. The mixture is cooled and toluene added with stirring. The resulting solid is filtered off, washed with toluene and dried to give N,N'-dicyclohexyl 3-(benzothiazol-2-ylthio)-1,2-propane dicarboxylic acid diamide, melting at 147°-49° C.

Workup

  1. temperatureThe mixture is cooled
  2. filtrationThe resulting solid is filtered off
  3. washwashed with toluene
  4. customdried

Sources & evidence

ORD record
ord-101e41552b85453a9ccd90b0a9aac5bd
Source dataset
uspto-grants-1988_01
Patent number
US04719036

Reaction notes

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