HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetic Anhydride → HCID 67361589, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetic Anhydride | HCID 7918 | — |
| Reactant | (15α)-13-Ethyl-15-hydroxygon-4-ene-3,17-dione | HCID 15513180 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 67361589 | HCID 67361589 | — |
Reaction Steps
200 ml of acetic anhydride is added dropwise to 100 g of 15α-hydroxy-18-methyl-4-estrene-3,17-dione in 350 ml of pyridine. After one hour, the reaction mixture is stirred into ice water. The thus-precipitated product is suctioned off, washed neutral with water, and dried under vacuum at 50° C., thus obtaining 100 g of 15α-acetoxy-18-methyl-4-estrene-3,17-dione. A sample recrystallized from acetone/hexane melts at 165° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04719054 |
| Source dataset | uspto-grants-1988_01 |
| ORD ID | ord-65a6a9582bba4209aaeb9cc3c4acf79d |
| Source note | uspto-grants-1988_01 |