2-Amino-2-methyl-1,3-propanediol → HCID 14370034, compound

HRID 2413618Notes

Reaction equation

HRID 2413618 reaction equation
[Cl:1][C:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([CH:16]=O)=[C:8]2[C:3]=1[CH:4]=[C:5]([CH3:19])[C:6]([CH3:18])=[CH:7]2.[CH3:20][C:21]([NH2:26])([CH2:24][OH:25])[CH2:22][OH:23]>>[ClH:1].[Cl:1][C:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([CH2:16][NH:26][C:21]([CH3:20])([CH2:24][OH:25])[CH2:22][OH:23])=[C:8]2[C:3]=1[CH:4]=[C:5]([CH3:19])[C:6]([CH3:18])=[CH:7]2

Participants

3

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 14370019HCID 14370019, compound

Product 1

HCID 14370034HCID 14370034, compound

Procedure

Using the reductive amination procedure outlined in 1, 10-chloro-2,3-dimethyl-9-anthracenecarbaldehyde and 2-methyl-2-amino-1,3-propanediol (Aldrich) gave 2-((10-chloro-2,3-dimethyl-9-anthracenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride mp 251°-252° (dec), (CH3OH/Et2O), (C,H,Cl,N).

Sources & evidence

ORD record
ord-aafe0eed00be4146a2e9440fd7020d6d
Source dataset
uspto-grants-1988_01
Patent number
US04719047

Reaction notes

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