2-Amino-2-methyl-1,3-propanediol → HCID 13375313, compound

HRID 2413620Notes

Reaction equation

HRID 2413620 reaction equation
[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH:16]=O)[C:8]3[C:13]([CH:14]=2)=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1.[CH3:18][C:19]([NH2:24])([CH2:22][OH:23])[CH2:20][OH:21]>CCO.CCOCC>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:6](=[C:7]([CH2:16][NH:24][C:19]([CH3:18])([CH2:22][OH:23])[CH2:20][OH:21])[C:8]3[C:13]([CH:14]=2)=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:15]=1

Participants

4

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 13375396HCID 13375396, compound

Product 1

HCID 13375313HCID 13375313, compound

Reagents, catalysts & solvents 1

HCID 21585056Diethyl ether ethanolSolvent

Procedure

Using the reductive amination procedure outlined in 1, 4-chloro-9-anthracenecarbaldehyde and 2-methyl-2-amino-1,3-propanediol (Aldrich) gave 2-((2-chloro-9-anthracenylmethyl)amino)-2-methyl-1,3-propanediol hydrochloride, mp 225°-226° (dec), (EtOH/Et2O), (C,H,Cl,N).

Sources & evidence

ORD record
ord-d71107510bd34c949de882a81a87903a
Source dataset
uspto-grants-1988_01
Patent number
US04719047

Reaction notes

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