2-Amino-2-methyl-1,3-propanediol → HCID 13375282, compound

HRID 2413627Notes

Reaction equation

HRID 2413627 reaction equation
[Cl:1][C:2]1[C:15]2[C:10](=[CH:11][CH:12]=[CH:13][CH:14]=2)[C:9]([CH:16]=O)=[C:8]2[C:3]=1[CH:4]=[CH:5][CH:6]=[CH:7]2.[NH2:18][C:19]([CH3:24])([CH2:22][OH:23])[CH2:20][OH:21]>>[ClH:1].[Cl:1][C:2]1[C:3]2[C:8](=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:9]([CH2:16][NH:18][C:19]([CH3:24])([CH2:22][OH:23])[CH2:20][OH:21])=[C:10]2[C:15]=1[CH:14]=[CH:13][CH:12]=[CH:11]2

Participants

3

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 8270310-Chloro-9-anthraldehyde

Product 1

HCID 13375282HCID 13375282, compound

Procedure

Using the reductive amination procedure outlined in 1, 10-chloroanthracene-9-carbaldehyde (Aldrich) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-(((10-chloro-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol hydrochloride mp 268°-269° (dec), (CH3OH/Et2O), (C, H, Cl, N).

Sources & evidence

ORD record
ord-5073a4c611a64c45bb1cba0800f04b5e
Source dataset
uspto-grants-1988_01
Patent number
US04719049

Reaction notes

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