反应详情

1-Chloroanthracene prepared from 1-chloroanthraquinone (Aldrich) by the method of H. O. House et al. (J. Org. Chem. 38. 1167 (1973)) was formylated by the procedure of A. Rieche et al., Chem. Ber. 93, 88 (1960). A mixture of a 1- and 4-chloro-9-anthracenecarbaldehydes was obtained which was partially purified by preparative HPLC using PhCH3 as the eluting solvent. The solid from the purified fraction was then recrystallized 2× from PhCH3 /CH3OH to give pure 4-chloro-9-anthracenecarbaldehyde mp 129°-131°, (C, H, Cl).

1. customwas obtained which
2. customwas partially purified by preparative HPLC
3. customThe solid from the purified fraction was then recrystallized 2× from PhCH3 /CH3OH