2-Amino-2-methyl-1,3-propanediol → HCID 13375304, compound

HRID 2413635Notes

Reaction equation

HRID 2413635 reaction equation
[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH:16]=O)[C:8]3[C:13]([CH:14]=2)=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1.[NH2:18][C:19]([CH3:24])([CH2:22][OH:23])[CH2:20][OH:21]>CCO.CCOCC>[ClH:1].[Cl:1][C:2]1[C:15]2[C:6](=[C:7]([CH2:16][NH:18][C:19]([CH3:24])([CH2:22][OH:23])[CH2:20][OH:21])[C:8]3[C:13]([CH:14]=2)=[CH:12][CH:11]=[CH:10][CH:9]=3)[CH:5]=[CH:4][CH:3]=1

Participants

4

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 13375396HCID 13375396, compound

Product 1

HCID 13375304HCID 13375304, compound

Reagents, catalysts & solvents 1

HCID 21585056Diethyl ether ethanolSolvent

Procedure

Using the reductive amination procedure outlined in 1, 4-chloro-9-anthracenecarbaldehyde (11A) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-(((4-chloro-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol hydrochloride, mp 225°-226° (dec), (EtOH/Et2O), (C, H, Cl, N).

Sources & evidence

ORD record
ord-b90621a7b89441f6b6bd41234013dd77
Source dataset
uspto-grants-1988_01
Patent number
US04719049

Reaction notes

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