2-Amino-2-methyl-1,3-propanediol → HCID 13375440, compound

HRID 2413644Notes

Reaction equation

HRID 2413644 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:14]([CH:15]=1)=[CH:13][C:12]1[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:6]=2[CH:16]=O.[NH2:18][C:19]([CH3:24])([CH2:22][OH:23])[CH2:20][OH:21]>CO.CCOCC>[ClH:1].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[C:14]([CH:15]=1)=[CH:13][C:12]1[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=1)[C:6]=2[CH2:16][NH:18][C:19]([CH3:24])([CH2:22][OH:23])[CH2:20][OH:21]

Participants

4

Reactant 2

HCID 15312-Amino-2-methyl-1,3-propanediolHCID 13375400HCID 13375400, compound

Product 1

HCID 13375440HCID 13375440, compound

Reagents, catalysts & solvents 1

HCID 21864698Diethyl ether methanolSolvent

Procedure

Using the reductive amination procedure outlined in 1, 3-chloro-9-anthracenecarbaldehyde (17B) and 2-amino-2-methyl-1,3-propanediol (Aldrich) gave 2-(((3-chloro-9-anthracenyl)methyl)amino)-2-methyl-1,3-propanediol hydrochloride mp 268°-269° (dec), CH3OH/Et2O, (C, H, Cl, N).

Sources & evidence

ORD record
ord-707674d4925841f7a990571da3bb2a2e
Source dataset
uspto-grants-1988_01
Patent number
US04719049

Reaction notes

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