HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl 3-(4-acetyl-2-methylphenyl)acrylate → Methyl 3-[4-[3-[3-butyl-6-(trifluoromethyl)benzothiophen-2-yl]propenoyl]-2-methylphenyl]acrylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl 3-(4-acetyl-2-methylphenyl)acrylate | HCID 66883900 | — |
| Reactant | 3-Butyl-6-(trifluoromethyl)benzothiophen-2-carboxaldehyde | HCID 86652865 | — |
| Product | Methyl 3-[4-[3-[3-butyl-6-(trifluoromethyl)benzothiophen-2-yl]propenoyl]-2-methylphenyl]acrylate | HCID 66884055 | — |
Reaction Steps
The titled compound was prepared from the above-mentioned 3-butyl-6-(trifluoromethyl)benzothiophen-2-carboxaldehyde (88 mg, 0.31 mmol) and methyl 3-(4-acetyl-2-methylphenyl)acrylate (67 mg, 0.31 mmol) in a procedure similar to that of Example 7 (1) as a yellow crystal (77 mg, yield 51%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08648208B2 |
| Source dataset | uspto-grants-2014_02 |
| ORD ID | ord-568702312e5c4c0e9e1272622354b0ab |
| Source note | uspto-grants-2014_02 |