Methanol → HCID 13990998, compound

Participants

Reaction Steps

1-3-methoxy 17-oxo estra 3,5-diene 10 g 3, 17-dioxo estra 4-ene in 50 ml methanol are mixed under stirring with 10 ml methyl orthoformate and 50 mg p. toluene sulphonic acid. Few drops of triethylamine are added thereto then the mixture is chilled and the crystalls are separated then dried--3-methoxy 17-oxo estra 3, 5-diene are thus obtained with a yield of 69%.

Provenance & Evidence