HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Hydroxy-2-(3-Methoxyphenyl)-6-Methoxynaphthalene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Acetyloxy-2-(3-Methoxyphenyl)-6-Methoxynaphthalene | HCID 12972207 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 1-Hydroxy-2-(3-Methoxyphenyl)-6-Methoxynaphthalene | HCID 12972208 | — |
Reaction Steps
A suspension was prepared of 46.5 g of 1-acetyloxy-2-(3-methoxyphenyl)-6-methoxynaphthalene and 40 mL of 5N HCl in 400 mL of MeOH. The reaction mixture was heated to reflux for eleven hours. The reaction mixture was evaporated to a clear oil. This yielded 38.6 g of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812244B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-051f06178e984adb8d497c6e9c52c663 |
| Source note | uspto-grants-2004_11 |