HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylamine → 6-chloro-N-isopropylnicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylamine | HCID 6363 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | 6-Chloronicotinic acid | HCID 79222 | — |
| Product | 6-chloro-N-isopropylnicotinamide | HCID 819369 | — |
Reaction Steps
The product was prepared from 6-chloro-nicotinic acid (1.0 g), carbonyldiimidazole (0.8 g) and isopropylamine (0.6 ml) using the method of example 115 step (i). Yield 0.75 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812226B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-e19bc57ace4540c9ae4f0e0941251e64 |
| Source note | uspto-grants-2004_11 |