HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(4-Piperidinyl)-1,2-dihydro-4H-3,1-benzoxazin-2-one hydrochloride → 3-Pyridinecarboxamide, 5-chloro-N-(1-methylethyl)-6-[4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)-1-piperidinyl]-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(4-Piperidinyl)-1,2-dihydro-4H-3,1-benzoxazin-2-one hydrochloride | HCID 22063089 | — |
| Reactant | 5,6-Dichloro-N-isopropylnicotinamide | HCID 22644601 | — |
| Product | 3-Pyridinecarboxamide, 5-chloro-N-(1-methylethyl)-6-[4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)-1-piperidinyl]- | HCID 22644568 | — |
Reaction Steps
The title compound was prepared from the product of step (i) (0.3 g) and 1-piperidin-4-yl-1,4-dihydro-2H-3,1-benzoxazin-2-one hydrochloride (0.35 g) using the method of example 115 step (ii). Yield 0.187 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812226B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-bfbc3115fdf3474c9601d1bee78f7455 |
| Source note | uspto-grants-2004_11 |