HuagongsheHuagongshe Chemistry Print Report · For research reference only
6-chloro-N-isopropylnicotinamide → 5-Chloro-n-(1-methylethyl)-6-[4-(4-methyl-2-oxo-2h-3,1-benzoxazin-1(4h)-yl)piperidin-1-yl]pyridine-3-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 6-chloro-N-isopropylnicotinamide | HCID 819369 | — |
| Reactant | 1-(4-Piperidyl)-4-methyl-3,1-benzoxazin-2-one hydrochloride | HCID 22644681 | — |
| Product | 5-Chloro-n-(1-methylethyl)-6-[4-(4-methyl-2-oxo-2h-3,1-benzoxazin-1(4h)-yl)piperidin-1-yl]pyridine-3-carboxamide | HCID 22644637 | — |
Reaction Steps
The title compound was prepared from the product of step (ii) (0.36 g) and the product from example 117 step (i) (0.466 g) using the method of example 115 step (ii). Yield 0.112 g
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812226B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-372703aa2407456fb403edf33930f71c |
| Source note | uspto-grants-2004_11 |