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HRID2414338

反应详情

EQUATION

反应方程式

HRID 2414338 的结构方程式

REACTANTS

反应物

3
结构：O=C(n1ccnc1)n1ccnc1
HCID68263

1,1'-Carbonylbis(1H-imidazole)

C7H6N4O

结构：C#CC(C)(C)N
HCID76319

3-Butyn-2-amine, 2-methyl-

C5H9N

结构：O=C(O)c1cnc(N2CCC(N3C(=O)OCc4ccccc43)CC2)c(Cl)c1
HCID22644584

未命名化合物

PRODUCTS

生成物

1
结构：C#CC(C)(C)NC(=O)c1cnc(N2CCC(N3C(=O)OCc4ccccc43)CC2)c(Cl)c1
HCID22644623

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from the product of example 148 step (i) (0.14 g), carbonyldiimidazole (0.064 g) and 1,1-dimethylpropargylamine (0.06 g) using the method of example 115 step (i). Purification was by chromatography eluting with ethyl acetate/isohexane (2/3). Yield 0.03 g as a solid.

WORKUP

后处理

  1. customPurification
  2. washeluting with ethyl acetate/isohexane (2/3)