HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Hydrochloric Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 4-Benzyloxy-3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile | HCID 22645146 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Hydrochloric Acid | HCID 313 | — |
| Product | 3-(2-Aminoethoxy)-4-benzyloxybenzonitrile | HCID 22645176 | — |
Reaction Steps
3.4 g (9.2 mmol) of 4-benzyloxy-3-[2-(t-butoxycarbonylamino)ethoxy]benzonitrile was dissolved in 40 ml of 4 N solution of hydrogen chloride in dioxane, and the obtained solution was stirred overnight. The solvent was evaporated to obtain hydrochloride of the crude title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06812231B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-6ccd5f608d5d43d5b8e922188263b6b5 |
| Source note | uspto-grants-2004_11 |