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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2414716Generated: October 30, 2026

3-Fluoropyridine → 2-(Pyridin-3-YL)octahydropyrrolo[3,4-C]pyrrole

https://huagongshe.com/reaction/2414716

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-FluoropyridineHCID 67794—
ReactantOctahydropyrrolo(3,4-c)pyrroleHCID 21867666—
Product2-(Pyridin-3-YL)octahydropyrrolo[3,4-C]pyrroleHCID 9942351—

Reaction Steps

Prepared by heating 3-fluoropyridine and 3.7-Diazabicyclo[3.3.0]octane in an autoclave in the absence of solvent at 180° C. for 24 hours. Workup-procedure A/B.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06815438B2
Source datasetuspto-grants-2004_11
ORD IDord-7771e4dc6270468b841ae7a45871a638
Source noteuspto-grants-2004_11