HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2,3-Difluorophenyl)-2-propenoic acid → 3-(2,3-difluorophenyl)propanoic Acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2,3-Difluorophenyl)-2-propenoic acid | HCID 2736961 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 3-(2,3-difluorophenyl)propanoic Acid | HCID 3799336 | — |
Reaction Steps
To a suspension of 2,3-difluoro-cinnamic acid (2.94 g, 16 mmol) in ethanol (100 mL) is added Pd (10% on carbon, 50 mg) and the mixture is treated with hydrogen (7.5 bar) for 15 h. The suspension is filtered through celite and the solvent evaporated to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06815451B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-c809bc499ab64bc1afa716d459617a42 |
| Source note | uspto-grants-2004_11 |