Ammonium Hydroxide → 2-Amino-n-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-5-yl)acetamide

HRID 241485Notes

Reaction equation

Cl[CH2:2][C:3]([NH:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[C:8](=[O:17])[NH:9][NH:10][C:11]2=[O:16])=[O:4].[OH-].[NH4+:19]>>[NH2:19][CH2:2][C:3]([NH:5][C:6]1[CH:15]=[CH:14][CH:13]=[C:12]2[C:7]=1[C:8](=[O:17])[NH:9][NH:10][C:11]2=[O:16])=[O:4]

Participants

Reactant 2

HCID 14923Ammonium Hydroxide

HCID 543576732-Chloro-N-(1,4-dioxo-1,2,3,4-tetrahydrophthalazine-5-yl)acetamide

Product 1

HCID 247112532-Amino-n-(1,4-dioxo-1,2,3,4-tetrahydrophthalazin-5-yl)acetamide

Procedure

forming a second reaction mixture comprising the 2-Chloro-N-(1,4-dioxo-1,2,3,4-tetrahydrophthalazine-5-yl)acetamide and ammonium hydroxide, to yield 2-Amino-N-(1,4-dioxo-1,2,3,4-tetrahydrophthalazine-5-yl)acetamide; and

Workup

customforming a second reaction mixture

Sources & evidence

ORD record: ord-6f7fc53e9c474e7f880f26ea3e9811b3
Source dataset: uspto-grants-2014_02
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08652442B2

Reaction notes

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