Trifluoroacetic anhydride → HCID 690641, compound

HRID 2414855Notes

Reaction equation

[CH3:1][O:2][C:3]1[CH:12]=[CH:11][C:6]([C:7]([NH:9][NH2:10])=[O:8])=[CH:5][CH:4]=1.[O:13](C(C(F)(F)F)=O)[C:14]([C:16]([F:19])([F:18])[F:17])=O>>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([C:7]([NH:9][NH:10][C:14](=[O:13])[C:16]([F:19])([F:18])[F:17])=[O:8])=[CH:11][CH:12]=1

Participants

Reactant 2

HCID 9845Trifluoroacetic anhydride

HCID 767924-Methoxybenzohydrazide

Product 1

HCID 690641HCID 690641, compound

Procedure

Synthesis and isolation were same as I-benzoyl-2-trifluoroacetylhydrazine, using 1.8 g (10.8 mmol) of 4-methoxybenzoylhydrazine and 2.0 g (9.5 mmol) of (CF3CO)2O. Yield was 2.4 g (85%). MS (EI, m/e) calcd for C10H9F3N2O3 262, found 262 (M+, 8.0); mp 147-148° C.

Workup

customSynthesis and isolation

Sources & evidence

ORD record: ord-b8458c1a9f174f88ad80a949f911f9e7
Source dataset: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06815528B2

Reaction notes

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