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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415156Generated: October 31, 2026

9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → 9-{4-[4-(5-Chloro-2-methoxy-phenyl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide

https://huagongshe.com/reaction/2415156

Reaction equation

Participants

RoleNameHCIDCharge
Reactant9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamideHCID 10526437—
Reactant1-(5-Chloro-2-methoxyphenyl)piperazine--hydrogen chloride (1/1)HCID 24206419—
Product9-{4-[4-(5-Chloro-2-methoxy-phenyl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amideHCID 22640156—

Reaction Steps

Prepared analogously to Example 2 b from 1-(5-chloro-2-methoxy-phenyl)-piperazine hydrochloride and 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06818644B1
Source datasetuspto-grants-2004_11
ORD IDord-43b652011c0e46de8af8ec84d0d868f7
Source noteuspto-grants-2004_11