HRID2415176

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID12200470

1-(6-Methoxypyridin-2-yl)piperazine

C10H15N3O

结构：O=C(NCC(F)(F)F)C1(CCCCBr)c2ccccc2Oc2ccccc21

HCID22180203

未命名化合物

PRODUCTS

生成物

结构：COc1cccc(N2CCN(CCCCC3(C(=O)NCC(F)(F)F)c4ccccc4Oc4ccccc43)CC2)n1

HCID22640151

未命名化合物

PROCEDURE

实验过程

Prepared analogously to Example 2 b from 1-(6-methoxy-pyridin-2-yl)-piperazine and 9-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-a26cd8fa2e914cc38a9b6d34e44e6de3
来源数据集: uspto-grants-2004_11
DOI: 10.6084/m9.figshare.5104873.v1
专利: US06818644B1
来源说明: uspto-grants-2004_11

反应 SMILES

[CH3:1][O:2][C:3]1[N:8]=[C:7]([N:9]2[CH2:14][CH2:13][NH:12][CH2:11][CH2:10]2)[CH:6]=[CH:5][CH:4]=1.[F:15][C:16]([F:41])([F:40])[CH2:17][NH:18][C:19]([C:21]1([CH2:35][CH2:36][CH2:37][CH2:38]Br)[C:34]2[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=2[O:28][C:27]2[C:22]1=[CH:23][CH:24]=[CH:25][CH:26]=2)=[O:20]>>[F:41][C:16]([F:15])([F:40])[CH2:17][NH:18][C:19]([C:21]1([CH2:35][CH2:36][CH2:37][CH2:38][N:12]2[CH2:13][CH2:14][N:9]([C:7]3[CH:6]=[CH:5][CH:4]=[C:3]([O:2][CH3:1])[N:8]=3)[CH2:10][CH2:11]2)[C:22]2[CH:23]=[CH:24][CH:25]=[CH:26][C:27]=2[O:28][C:29]2[C:34]1=[CH:33][CH:32]=[CH:31][CH:30]=2)=[O:20]