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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415176Generated: October 26, 2026

1-(6-Methoxypyridin-2-yl)piperazine → 9-{4-[4-(6-methoxy-pyridin-2-yl)-piperazin-1-yl]-butyl}-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide

https://huagongshe.com/reaction/2415176

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(6-Methoxypyridin-2-yl)piperazineHCID 12200470—
Reactant4-[9-(2,2,2-Trifluoroethylcarbamoyl)-9H-xanthen-9-yl]butyl bromideHCID 22180203—
Product9-{4-[4-(6-methoxy-pyridin-2-yl)-piperazin-1-yl]-butyl}-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amideHCID 22640151—

Reaction Steps

Prepared analogously to Example 2 b from 1-(6-methoxy-pyridin-2-yl)-piperazine and 9-(4-bromo-butyl)-9H-xanthene-9-carboxylic acid-(2,2,2-trifluoroethyl)-amide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06818644B1
Source datasetuspto-grants-2004_11
ORD IDord-a26cd8fa2e914cc38a9b6d34e44e6de3
Source noteuspto-grants-2004_11