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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415252Generated: October 31, 2026

4-Bromo-1-ethenyl-2-fluorobenzene → 4-Bromo-1-ethyl-2-fluorobenzene

https://huagongshe.com/reaction/2415252

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Bromo-1-ethenyl-2-fluorobenzeneHCID 16660774—
CatalystPalladiumHCID 23938—
SolventEthyl AcetateHCID 8857—
Product4-Bromo-1-ethyl-2-fluorobenzeneHCID 22641057—

Reaction Steps

4-Bromo-2-fluoro-1-vinyl-benzene (1.80 g, 8.96 mmol) was dissolved in ethyl acetate (50 mL) and palladium-on-carbon (10%, 70 mg) was added and the mixture was hydrogenated under 1 atmosphere overnight. The mixture was filtered and the filtrate was concentrated to give the crude, 1.80 g, which was used directly for the next step.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06818663B2
Source datasetuspto-grants-2004_11
ORD IDord-59db2a2efae84a179b953dc86a8ba6c1
Source noteuspto-grants-2004_11