Potassium Carbonate → HCID 22641889, compound

Participants

Reaction Steps

The 5-hydroxy-1-indanone (20 g, 134.9 mmol) was solved in dry in N,N′-dimethylformamide (120 mL) and the 4-fluorobenzyl bromide (18.2 mL, 148.4 mmol) was added followed by potassium carbonate anhydrous (24.2 g, 175.4 mmol) and the mixture was stirred for 12 h to 110 IC. Water was added and the resulting precipitate was filtrated and dried (34.6 g, 100%). MS: m/e=256.1 (M+).

Provenance & Evidence