Hydrochloric Acid → Hydrochloric Acid

Participants

Reaction Steps

In analogy to example 3, from 2-methyl-4-pyrrolidin-1-yl-quinolin-7-ol, product of example 2, and cyclopropylmethyl bromide—with reaction times of 19 h (0° C.) and isolation of the product as hydrochloride, via treatment of the reaction product with HCl-saturated diethyl ether—there was obtained 7-cyclopropylmethoxy-2-methyl-4-pyrrolidin-1-yl-quinoline hydrochloride as a white solid. ISP mass spectrum, m/e: 283.2 (M+1 calculated for C18H22N2O: 283).

Provenance & Evidence