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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2415468Generated: October 31, 2026

Picolyl chloride → HCID 22641302, compound

https://huagongshe.com/reaction/2415468

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPicolyl chlorideHCID 23393—
Reactant2-Methyl-4-pyrrolidin-1-yl-quinolin-7-olHCID 135804118—
ProductHCID 22641302HCID 22641302—

Reaction Steps

In analogy to example 6 there was prepared: on reaction of 2-methyl-4-pyrrolidin-1-yl-quinolin-7-ol with 2-picolyl choride, whereby the product was isolated as free base, 2-methyl-7-(pyridin-2-ylmethoxy)-4-pyrrolidin-1-yl-quinoline as a light brown solid. ISP mass spectrum, m/e: 320.4 (M+1 calculated for C20H21N3O: 320).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06818767B2
Source datasetuspto-grants-2004_11
ORD IDord-1ff48f01a7c243d8831e029c648f928f
Source noteuspto-grants-2004_11