HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzonitrile, 4-bromo- → 4-(2-Methyl-4-pyrrolidin-1-yl-quinolin-7-yloxy)-benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzonitrile, 4-bromo- | HCID 12162 | — |
| Reactant | 2-Methyl-4-pyrrolidin-1-yl-quinolin-7-ol | HCID 135804118 | — |
| Product | 4-(2-Methyl-4-pyrrolidin-1-yl-quinolin-7-yloxy)-benzonitrile | HCID 22641445 | — |
Reaction Steps
In analogy to example 6 there was prepared: on reaction of 2-methyl-4-pyrrolidin-1-yl-quinolin-7-ol with 4-bromobenzonitrile, whereby the product was isolated as free base, 4-(2-methyl-4-pyrrolidin-1-yl-quinolin-7-yloxy)-benzonitrile as a white solid. ISP mass spectrum, m/e 330.5 (M+1 calculated for C21H19N3O: 330).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06818767B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-7c5a82aefd504c80aa6fcd08c462bd81 |
| Source note | uspto-grants-2004_11 |