Cyclobutylamine → N-cyclobutyl-3-(3,4-dimethoxybenzamido)-4-methylbenzamide

HRID 2415707Notes

Reaction equation

HRID 2415707 reaction equation
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:19]=[CH:20][C:21]=1[O:22][CH3:23])[C:6]([NH:8][C:9]1[CH:10]=[C:11]([CH:15]=[CH:16][C:17]=1[CH3:18])[C:12]([OH:14])=O)=[O:7].[CH:24]1([NH2:28])[CH2:27][CH2:26][CH2:25]1>>[CH:24]1([NH:28][C:12](=[O:14])[C:11]2[CH:15]=[CH:16][C:17]([CH3:18])=[C:9]([NH:8][C:6](=[O:7])[C:5]3[CH:19]=[CH:20][C:21]([O:22][CH3:23])=[C:3]([O:2][CH3:1])[CH:4]=3)[CH:10]=2)[CH2:27][CH2:26][CH2:25]1

Participants

3

Reactant 2

HCID 75645CyclobutylamineHCID 36001793-[(3,4-Dimethoxybenzoyl)amino]-4-methylbenzoic acid

Product 1

HCID 22636138N-cyclobutyl-3-(3,4-dimethoxybenzamido)-4-methylbenzamide

Procedure

Using an analogous procedure to that described in Example 8, 3-(3,4-dimethoxybenzamido)-4-methylbenzoic acid was reacted with cyclobutylamine to give the title compound; Mass Spectrum: M+H+ 369.

Sources & evidence

ORD record
ord-2eba9230b483402f94044fb9aefeb477
Source dataset
uspto-grants-2004_11
Patent number
US06821965B1

Reaction notes

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