Sodium Hydroxide → HCID 22636735, compound

Participants

Reaction Steps

9-[(1H-indole-2-carbonyl)amino]-3,4-dihydro-2H-benzo[b][1,4]dioxepine-6-carboxylic acid methyl ester (E-2; R=H; 50 mg) was combined with 1 mL of THF and 1 mL of 1M NaOH and the reaction stirred for 4 days at room temperature. The solid was collected on a filter to yield 23 mg of a solid. LCMS: AP+ 353.

Provenance & Evidence