HuagongsheHuagongshe Chemistry Print Report · For research reference only
9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide → 9-{4-[4-(5-chloro-quinoxalin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 9-(4-Bromobutyl)-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide | HCID 10526437 | — |
| Reactant | 5-Chloro-2-piperazin-1-yl-quinoxaline | HCID 12686427 | — |
| Product | 9-{4-[4-(5-chloro-quinoxalin-2-yl)-piperazin-1-yl]-butyl}-9H-fluorene-9-carboxylic Acid-(2,2,2-trifluoro-ethyl)-amide | HCID 22636234 | — |
Reaction Steps
Prepared analogously to Example 2 from 9-(4-bromo-butyl)-9H-fluorene-9-carboxylic acid-(2,2,2-trifluoro-ethyl)-amide and 5-chloro-2-piperazin-1-yl-quinoxaline Melting point: 74° C. C32H31ClF3N5O (M=594.08) Calc.: molecular peak (M+H)+: 594/596. Found: molecular peak (M+H)+: 594/596.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06821967B2 |
| Source dataset | uspto-grants-2004_11 |
| ORD ID | ord-84682c1e2b5e4ff88a7c76cf68fa360e |
| Source note | uspto-grants-2004_11 |