Piperazine → 8-Bromo-2-(piperazin-1-yl)quinoline

HRID 2415892Notes

Reaction equation

HRID 2415892 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9](Cl)[CH:8]=[CH:7]2.[NH:13]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]1>>[Br:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([N:13]1[CH2:18][CH2:17][NH:16][CH2:15][CH2:14]1)[CH:8]=[CH:7]2

Participants

3

Reactant 2

HCID 4837PiperazineHCID 109557558-Bromo-2-chloroquinoline

Product 1

HCID 226362718-Bromo-2-(piperazin-1-yl)quinoline

Procedure

Prepared analogously to Example 3 from 8-bromo-2-chloro-quinoline and piperazine.

Sources & evidence

ORD record
ord-0c34c5182af246a89ffd131d95771cd4
Source dataset
uspto-grants-2004_11
Patent number
US06821967B2

Reaction notes

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